Recently we have had many problems with the Nutro Natural Choice. There has been 2 puppies we have had that have had Anemia. This is not something we have ever experienced before. Doing a lot of research we have found that the Nutro Natural Choice can cause Anemia, as well as some liver and kidney issues. If you have a puppy from us on the Nutro Natural Choice, we are switching our dogs back over to the Blue Buffalo, Chicken and Rice Adult and Puppy formulas (Blue bag for adults, light blue for puppies.) If your dog is on another food, you do not need to worry about this. For the first week, mix the two foods half and half, then just the Blue, 1/3 a cup 2x a day. You will find your dog does not need as much food with the Blue because of all the vitamins and nutrients in the Blue Buffalo. For any questions or concerns please feel free to email, or call us. Anemia is NOT genetic, it is a cause of the food.